Project 127: Practice and Training of Biotechnology and Antibody Medicine

Contact Information:

Assoc. Prof. Feng Qian

Project Description and Objectives:

Antibodies are ideal for therapeutic interventions in part owing to their high specificity, high tolerance, long half-life and amenability to manipulation. Antibody-based therapeutics is at the center stage of drug discovery with antibodies being the fastest growing class of drugs. In this project, we will prepare detection antibodies and therapeutic antibodies using mouse hybridoma technology, phage display technology, antibody humanization technology and engineered cell expression antibody technology. We also plan to develop new antibody drugs that regulate inflammation and control tumors, and prepare new CAR-T cells to treat tumors and immune diseases.

Eligibility Requirements:

Basic biology and basic molecular cell biology.

Main Tasks:

Understand goals of the project.

Generate monoclonal or bi-specific antibody, manipulate tumor cell culture and do antitumor testing.

Report–Analyze-Present your data in PPT format.

Website:

Lab: https://pharm.sjtu.edu.cn/ktz/2811.html

School: https://pharm.sjtu.edu.cn/