Project 118: The Role of Macrophage During the Very Early Stage of Tumor Progression

Contact Information:

Assoc. Prof. Donglei Sun

Project Description and Objectives:

Tumors are one of the biggest challenges to human health, the metastasis of which threatens the lives of millions. Macrophage contributes significantly to the development of tumors, but how macrophage and other myeloid cells interact with a tumor at the very early stage is unknown. In this research project, we use intravital microscopy and other related immunological approaches to address the development of tumor-associated macrophage and characterize their functions.

Eligibility Requirements:

Responsible undergraduate students following lab rules are welcome.

GPA ≥ 3.0 in a 4.0 scoring system, or ≥80 in a 100 scoring system.

Main Tasks:

Learn about fluorescence microscope and macrophage;

Learn to analyze macrophage population by flowcytometry and immunofluorescence; 3) Creation of tumor models;

Macrophage depletion and function evaluation;

Essay writing.

Website:

Lab: https://life.sjtu.edu.cn/teacher/En/dongleisun

School: https://life.sjtu.edu.cn/En