Project 115: Research of Genomics Analysis and Genetic Mechanism of Complex Diseases

Contact Information:

Prof. Yongyong Shi

Project Description and Objectives:

This lab is focusing on developing new analytical tools for genetic studies, and discovering new genetic mechanisms of cancers, mental disorders, heart diseases and endocrine diseases. The major research interests include: (1) development of new experimental methods and data analysis algorithms in molecular genetics; (2) identification of common/rare variants associated with complex diseases such as schizophrenia by genome-wide association studies; (3) perform in vivo and in vitro functional studies for novel mutations to reveal their exact pathogenic mechanisms; (4) development of the correlated new drug and/or minimally invasive diagnosis for target therapies. Through this research, we aim to identify risk genes, pathways and mechanisms of drug action for complex diseases and contribute to precision medicine in the near future.

Eligibility Requirements:

Basic knowledge of genetics, statistics and molecular biology.

Main Tasks:

Bioinformatics

Chip/sequencing data analysis

In vivo/vitro functional experiments

Website:

Lab: http://www.bio-x.cn

School: http://life.sjtu.edu.cn