Project 84: bFGF Genetically Engineered Endothelial Progenitor Cells for Ischemic Stroke Treatment
Contact Information:
Prof. Yongting Wang
Email: ytwang@sjtu.edu.cn
Project Description and Objectives:
Stem cells are being tested in several clinical trials for the treatment of Ischemic Stroke. The genetic engineering of stem cells takes advantage of the stem cells not only as a therapeutic moiety but also as a factory and cargo for the gene product. In addition, genetic modification of stem cells can also augment the survival and function of the transplanted stem cells. Previously, our lab had identified that bFGF plays a key role in tissue protection after ischemic insult. In this project, we aim to investigate the potential of the bFGF genetically engineered endothelial progenitor cells in treating ischemic injury. The students will join a team of graduate students and research faculty members. Techniques used in this project will include but not be limited to stem cell culture, exosome preparation, animal surgery, and data analysis.
Eligibility Requirements:
Must be at least in their sophomore year.
Skills desirable but not required: cell culture, molecular cloning.
Main Tasks
Attend weekly lab meetings and carry out experiments.
Give two research presentations. (one on literature review, one on research progress)
Finish a research report.
Website:
School: http://bme.sjtu.edu.cn/