Project 121: Design, Synthesis and Biological Evaluation of KRAS-targeting Antitumor Drugs

Contact Information:

Asso. Prof. Faqin Jiang

Email: jfq2008@sjtu.edu.cn

Project Description and Objectives:

KRAS has emerged as a promising target in the treatment of solid tumors. However clinically viable inhibitors have yet to be identified. We will design and synthesize KRAS-targeting inhibitors based on the structure of this protein, and evaluate their antitumor activities.

Eligibility Requirements:

Basic knowledge on chemistry or biology.

Main Tasks:

Chemical synthesis of compounds; biological experiments.

Website: 

Lab: N/A

School: http://pharm.sjtu.edu.cn/en