Project 85: Developing Molecular Probes for Tracking Stem Cell Derived Exosomes in Live Animals
Contact Information:
Asso. Prof.Yaohui Tang
Email: yaohuitang@sjtu.edu.cn
Project Description and Objectives:
Stem cell derived exosomes were beneficial for treating Ischemic Stroke, which is the major cause of disability and the second cause of death worldwide. However, quantitatively tracking exosomes and investigating their therapeutic efficacy and mechanism are still challenging. This project aims to develop multi-functional molecular probes to dynamically track exosomes that are intravenously or intra-arterially injected into mice as well as explore their therapeutic efficacy and underlying mechanisms. The students will join a team of graduate students and research faculty members. Techniques used in this project will include but not be limited to stem cell culture, exosome preparation, animal surgery, and data analysis.
Eligibility Requirements:
Must be at least in their sophomore year.
Skills desirable but not required: cell culture.
Main Tasks:
Attend weekly lab meetings and carry out experiments.
Give two research presentations (one on literature review, one on research progress).
Test 2-3 molecular probes.
Finish a research report.
Website:
School: http://bme.sjtu.edu.cn/